Bordoli, Mattia
Oberassistent
Research Unit of Prof. Sabine Werner, Institute of Molecular Health Sciences, Swiss Federal Institute of Technology ETH
Institute of Molecular Health Sciences, Swiss Federal Institute of Technology ETH Zurich

Lab website: http://www.mhs.biol.ethz.ch/research/werner/group-members-werner/bordoli.html
Research interests: Regulation of extracellular matrix remodeling in health and disease.
Expertise: Secreted kinases, extracellular phosphorylation, fibrosis, tumor invasion, regeneration, wound healing

Ewald, Collin

Assistant Professor

Extracellular Matrix Regeneration Laboratory, Department of Health Sciences and Technology, ETH Zürich

Lab website: http://ewaldlab.com

CV on LinkedIn, Twitter: @CollinEwald

Research interests: Our recent work has shown that many health- and longevity-promoting interventions re-activate the expression of extracellular matrix (ECM) genes during aging (Ewald et al., Nature 2015, PMID:25517099). This ECM enhancement is required and sufficient for extending the lifespan of C. elegans. Our research efforts are focusing on exploring the mechanism(s) of how prolonged ECM homeostasis promotes healthy aging.

Expertise: C. elegans ECM, aging, protein aggregation, neurodegeneration (Alzheimer's disease), Insulin/IGF-1 signaling, NADPH oxidases, ROS, oxidative stress.

Giunta, Cecilia

Oberassistent

Division of Metabolism, Connective Tissue Unit, University Children's Hospital Zurich
Lab website: http://www.kispi.uzh.ch/fzk/de/abteilungen/uebersicht/stoffwechsel/Seiten/angeborene-bindegewebskrankheiten.aspx
CV on http://orcid.org/0000-0002-9313-8257

Research interests: Improve the understanding of the pathomorphogenesis of the inherited connective tissue disorders Ehlers-Danlos Syndrome and Osteogenesis Imperfecta. Role of collagen folding, secretion, assembly and extracellular matrix homeostasis in health and disease.

Expertise: Collagen, ER-stress, Ehlers-Danlos Syndrome, Osteogenesis imperfecta, disease variants.

Mazza, Edoardo
Professor
Institute for Mechanical System, Department of Mechanical and Process Engineering, ETH Zürich
Lab website: http://www.zfm.ethz.ch/e/biomechanics/
CV: http://www.imes.ethz.ch/people/Prof-Dr-Edoardo-Mazza.html

Research interests: Experimental continuum mechanics, applied for the solution of challenging problems in engineering and medicine. The deformation mechanisms of soft biological tissues in human organs is characterized at all relevant length scales and is described with appropriate mathematical models. Knowledge of tissues properties is used for diagnosis, and for biomedical simulations. Tissue engineered and synthetic biomedical materials, mesh implants, and cardiovascular prosthetic devices are evaluated in terms of “mechanical biocompatibility”. See also: www.hochschulmedizin.uzh.ch/zurichheart, www.hochschulmedizin.ch/skintegrity.

Expertise: Multiaxial in-situ and in-vivo biomechanical testing, traction force microscopy, cell-matrix interaction, chemo-mechanical coupling, fracture mechanics of soft collagenous tissues, multiphase continuum models, discrete fiber network models.

Moeller, Jens
Oberassistent
Research Unit of Prof. Viola Vogel, Laboratory of Applied Mechanobiology, Department of Health Sciences and Technology, ETH Zürich
Lab website: http://www.appliedmechanobio.ethz.ch/the-laboratory/people/scientific-assistants/Jens0.html
CV on LinkedIn
Research interests: We develop advanced 2D/3D culture platforms to study how the biochemical and physical properties of the cellular microenvironment affect cell and microtissue function, with particular focus on the mechanical aspects of immune cells/tissue - bacteria interactions.
Mechanotransduction, biophysics, surface functionalization, biomaterials.
Expertise: microfabrication, in vitro 2D/3D cell culture systems, advanced light microscopy, AFM, microfluidics, image analysis.

Raghunath, Michael
Professor
Cell Biology & Tissue Engineering, Institute for Chemistry and Biotechnology (ICBT), Zurich University of Applied Sciences
Lab websites: www.tissuemodulation.com; www.zhaw.ch
CV on LinkedIn
Research interests: Applied matrix biology using macromolecular crowding.
Collagen, fibrillin, heritable connective tissue disorders, stem cell microenvironment, brown fat differntiation, mesenchymal progenitor cells.
Expertise: adult stem cell differentiation, dermatology, matrix biology

Snedeker, Jess
Professor
University and ETH Zürich
Lab website: www.biomechanics.ch
Research interests: Collagen, Tendon, Advanced Glycation Endproducts.
Expertise: Biomechanics, Biophysics, Collagen, Tendon, Musculoskeletal Science, Biomedical Engineering

Werner, Sabine
Professor
Institute for Molecular Health Sciences, Department of Biology, ETH Zürich
Lab website: http://www.mhs.biol.ethz.ch/research/werner/research-werner.html
Research interests: Tissue injury initiates a series of events, which lead to at least partial reconstruction of the affected body site. Many conditions are associated with impaired tissue repair, including old age, steroid treatment and chronic diseases such as diabetes and cancer. A prerequisite for the improvement of impaired healing is a thorough understanding of the underlying cellular and molecular mechanisms. Our laboratory studies these mechanisms, focusing on the roles of growth factors and reactive oxygen species in the repair process. One of the most exciting aspects of our work is the analysis of the parallels between tissue repair and cancer. We use state-of-the art approaches, including functional genomics and proteomics, 2D and 3D primary cell culture systems, and genetically modified mice for our research. Through collaboration with clinical partners we determine the importance of our findings for the human situation (see also SKINTEGRITY - a flagship project of "Hochschulmedizin Zurich", which is chaired by Sabine Werner - www.hochschulmedizin.ch/skintegrity).

Keynote Speaker of the SSMB 2019 Annual Meeting

Wolfrum, Christian

Professor
Translational Nutrition Biology, Department of Health Sciences and Technology, ETH Zürich

Lab website: http://www.tnb.ethz.ch/

Research interests: Adipocyte formation and function. Adipocyte Biology, brown adipocyte, white adipocyte, metabolism.
Expertise: molecular biology, physiology.

Wuetz-Kozak, Karin

Professor
Immunoengineering & Regenerative Medicine, Department of Health Sciences and Technology, ETH Zürich

Lab website: http://www.immunoreg.ethz.ch/

CV on personal website

Research interests: Understanding pathobiological processes; modulating inflammation and inducing regeneration in various tissues; mechanotransduction, TRP channels; inflammation; tissue degeneration and remodeling; interaction between resident cells and bacteria; smart biomaterials.
Expertise: electrospinning; immunomodulation; cell/molecular biology; inflammatory pathways; mechanical stimulation; TRP channels; biodrug.

Vogel, Viola
Professor
Laboratory of Applied Mechanobiology, Department of Health Sciences and Technology, ETH Zürich
Lab website: http://www.appliedmechanobio.ethz.ch/
Research interests: Mechanobiology of the extracellular matrix. Exploiting nanotechnology tools to decipher how bacteria and mammalian cells and micro-tissues exploit mechanical forces to recognize and respond to material properties and to their native environments.
Expertise: Applied mechanobiology, nanotechnology, molecular dynamics simulations, molecular tension probes, super-resolution microscopy, electron microscopy, traction force microscopy, and substrate patterning and functionalization.
Keynote Speaker of the SSMB 2017 Annual Meeting

Yalak, Garif

Oberassistent
Research Unit of Prof. Viola Vogel, Laboratory of Applied Mechanobiology, Department of Health Sciences and Technology, ETH Zürich
Lab website: http://www.appliedmechanobio.ethz.ch/
Research interests: Secreted kinases and extracellular phosphorylation.
Expertise: bioinformatics, computational biology, personalized health

Zenobi-Wong, Marcy

Professor

Tissue Engineering and Biofabrication, Department of Health Sciences and Technology, ETH Zürich

Lab website: www.biofabrication.ethz.ch

Twitter: @ZenobiWongLab

Research interests: Cartilage tissue engineering and regeneration.

Expertise: Cartilage matrix, scaffolds, tissue engineering, inflammation, biomaterials, bioprinting, growth factors.